Scientific Publications

The Irma and Paul Milstein Program for Senior Health: 52

1. Yiyin Chen, Sean X. Global calling to develop geroscience research and promote healthy aging—Key discussion points from the International Geroscience Symposium in Shenzhen, China. Aging Medicine. 2019.
2. Sean X. Leng, Baohua Liu, Brian K. Kennedy. Aging mechanisms and interventions that impact senior health: Introduction to a special issue on Geroscience. Aging Medicin3e.
3. Sean X. Leng, Brian K Kennedy. International Investment in Geroscience. Public Policy & Aging Report. 2019; 29 (4): 134-138.
4. Lina Ma. Current Situation of Frailty Screening Tools for Older Adults. The journal of nutrition, health & aging. 2019; 23(1): 111–118.
5. Lina Ma, Zhe Thang, P Chan, Jeremy Walston. Novel Frailty Screening Questionnaire (FSQ) Predicts 8-year Mortality in Older Adults in China. The Journal of Frailty & Aging, 2018; 8(1): 33-38.
6. Lina Ma, Fei Sun, Zhe Tang. Social frailty is associated with physical functioning, cognition, and depression, and predicts mortality. The journal of nutrition, health & aging.2018, 22(8):989-995.
7. Lina Ma, H. Niu, Guiming Sha, Yaxin Zhang, P. Liu, and Yun Li. Serum SIRT1 is Associated with Frailty and Adipokines in Older Adults. The Journal of Nutrition, Health & Aging. 2019; 23 (3): 246-250.
8. Lina Ma, Li Zhang, Fei Sun, Yun Li, Zhe Tang. Frailty in Chinese older adults with hypertension: prevalence, associated factors and prediction for long-term mortality. The Journal of Clinical Hypertension. 2018; 20(11): 1595-602.
9. Lina Ma, Guiming Sha, Yaxin Zhang, and Yun Li. Elevated serum IL-6 and adiponectin levels are associated with frailty and physical function in Chinese older adults. Clinical Interventions in Aging, 2018, 13: 2013-20.
10. Jintang Wang, Zheng Chen, Sean X. Leng. Interferon-γ potentiates α-synuclein-induced neurotoxicity linked to toll-like receptor 2 & 3 and tumor necrosis factor-α in murine astrocytes. Molecular Neurobiology, (accepted).
11. Juliette Tavenier, Joseph B. Margolick, Sean X. Leng. T-cell immunity against cytomegalovirus in HIV infection and aging: relationships with inflammation, immune activation, and frailty. Medical Microbiology and Immunology, (accepted).
12. Juliette Tavenier, Sean X. Leng. Inflammation pathways to anemia in frail older adults. Clinics in Geriatric Medicine, (accepted).
13. Hong Hong, Qi Wang, Jing Li, Hans Liu, Xin Meng, and Haiyan Zhang. Aging, Cancer and Immunity. Journal of Cancer. 2019; 10 (13): 3021-3027.
14. Sean X. Leng, Haiyan Zhang, Linda P. Fried. Inflammatory Markers and Frailty. Handbook of Immunosenescence, 2019: 1-14.
15. Yiyin Chen, Sally Liu, Sean X. Leng. Chronic Low-grade Inflammatory Phenotype (CLIP) and Senescent Immune Dysregulation. Clinical Therapeutics, 2019 (Article in Press).
16. Baoliang Zhong, Xiujun Liu, Wencai Chen, Helen Fungkum Chiu, Yeates Conwell. Loneliness in Chinese older adults in primary care: prevalence and correlates. Psychogeriatrics The Official Journal of The Japanese Psychogeriatric Society. 2018; 18 (5): 334-342.
17. Jintang Wang, Yuetao Song, Zheng Chen, Sean X. Leng. Connection between Systemic Inflammation and Neuroinflammation Underlies Neuroprotective Mechanism of Several Phytochemicals in Neurodegenerative Diseases. Oxidative Medicine and Cellular Longevity, 2018; 2018: 1-16.
18. Sean X. Leng, Xiaoying Li. Introduction of Abstracts to be Presented at the Seventh Chinese Congress on Gerontology and Health Industry. Journal of the American Geriatric Society, 2018; 66: s441- s442.
19. Waijiao Cai, Danielle Feng, Michael A. Schwarzschild, Pamela J. McLean, Xiqun Chen. Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice. EBioMedicine, 2018; 29: 13–22.
20. Xin Li, Li Fan, Sean X. Leng. The Aging Tsunami and Senior Healthcare Development in China. Journal of American Geriatrics Society, 2018; 66 (8): 1462 – 1468.
21. Maryam Keshtkar-Jahromi, Min Ouyang, Marzieh Keshtkarjahromi, Samah Almed, Huifen Li, Jeremy D. Walson, Rebeca Rios, Sean X. Leng. Effect of influenza vaccine on Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in older adults. Vaccine, 2018; 36 (16): 2220 – 2225.
22. Jintang Wang, Zheng Chen, Jeremy D. Walson, Peisong Gao, Maolong Gao, Sean X. Leng. α-Synuclein activates innate immunity but suppresses interferon-γ expression in murine astrocytes. European Journal of Neuroscience, 2018:1–17.
23. Joseph B. Margolick, Jay H. Bream, Tricia L. Nilles, Huifen Li, Susan J. Langan, Shane Deng, Ruibin Wang, Nikolas Wada, Sean X. Leng. Relationship between T-Cell Responses to CMV, Markers of Inflammation, and Frailty in HIV-uninfected and HIVinfected Men in the Multicenter AIDS Cohort Study. The Journal of Infectious Diseases, 2018; 218 (2): 1-10.
24. Jinlei Li, Matthew Ogrodnik, Vijaya B. Kolachalamad, Honghuang Lin, Rhoda Au. Assessment of the Mid-Life Demographic and Lifestyle Risk Factors of Dementia Using Data from the Framingham Heart Study Offspring Cohort. Journal of Alzheimer’s Disease, 2018; 63 (3):1119–1127.
25. Jinlei Li, Matthew Ogrodnik, Sherral Devine, Sanford Auerbach, Philip A. Wolf, Rhoda Au. Practical risk score for 5-, 10-, and 20-year prediction of dementia in elderly persons: Framingham Heart Study. Alzheimer’s & Dementia, 2018; 14 (1): 35 – 42.
26. Xiang Ding, Yong He, Qiukui Hao, Shanping Chen, Ming Yang, Sean X. Leng, Jirong Yue, Birong Dong. The association of single nucleotide polymorphism rs189037C>T in ATM gene with coronary artery disease in Chinese Han populations: A case control study. Medicine, 2018; 97(4) : e9747
27. Liye Shi, Jiang Liu, Lujiao Yu, Yiming Lei, Sean X. Leng, and Haiyan Zhang. Clinic-pathologic Features and Prognostic Analysis of Thyroid Cancer in the Older Adult: A SEER Based Study. Journal of Cancer. 2018; 9 (15): 2744-2750.
28. Jing Tang, Hans B. Liu, Lujiao Yu, Xin Meng, Sean X. Leng, Haiyan Zhang. Clinical-pathological Characteristics and Prognostic Factors for Papillary Thyroid Microcarcinoma in the Elderly. Journal of Cancer, 2018; 9 (2): 256–262.
29. Junhong Zhou, On-Yee Lo, Lewis A. Lipsitz, Jue Zhang, Jing Fang, Brad Manor. Transcranial direct current stimulation enhances foot sole somatosensation when standing in older adults. Experimental Brain Research, 2018; 236 (3):795-802.
30. Jintang Wang, Sean X. Leng. Inflammation and its role in ageing and disease. Oxford Textbook of Geriatric Medicine, 2018(3).
31. Xiqun Chen, Hongxiang Chen, Waijiao Cai, Michael Maguire, Bailiu Ya, Fuxing Zuo, Robert Logan, Hui Li, Katey Robinson, Charles R. Vanderburg, Yang Yu, Yinsheng Wang, David E. Fisher, Michael A. Schwarzschild. The Melanoma- Linked “Redhead” MC1R Influences Dopaminergic Neuron Survival. Annals of Neurology, 2017; 81(3):395–406.
32. Xiang Ding, Qiukui Hao, Ming Yang, Tie Chen, Shanping Chen, Jirong Yue, Sean X. Leng, Birong Don Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study. BMC Medical Genetics, 2017; 18 (84): 1-7.
33. Xinwen Zhang, Xin Meng, Yiyin Chen, Sean X. Leng, Haiyan Zhang. The Biology of Aging and Cancer Frailty, Inflammation, and Immunity. The Cancer Journal, 2017; 23 (4): 201 – 205.
34. Mingfang Zhao, Hans Liu, Yanqing Tang, Xin Meng, Jun Yu, Qi Wang, Qiao Zhou, Sean X. Leng, Haiyan Zhang. Clinicpathologic features and prognostic factors for patients with colorectal cancer who are 75 years and older. Oncotarget, 2017; 8 (45): 80002 – 80011.
35. Sean X. Leng, Xiao Ying Li. Introduction of Abstracts to be Presented at the Sixth Chinese Congress on Gerontology and Health Industry. Journal of the American Geriatric Society, 2017; 65 (s2): s293- s294.
36. Gregory D. Kirk, Stewart Dandorf, Huifen Li, Yiyin Chen, Shruti H. Mehta, Damani A. Piggott, Joseph B. Margolick, Sean X. Leng. Differential Relationships among Circulating Inflammatory and Immune Activation Biomediators and Impact of Aging and Human Immunodeficiency Virus Infection in a Cohort of Injection Drug Users. Frontiers in Immunology, 2017; 8:1343.
37. Sean X. Leng, Jeremy Kamil, John G. Purdy, Niels A. Lemmermann, Matthias J. Reddehase, Felicia D. Goodrum. Recent advances in CMV tropism, latency, and diagnosis during aging. GeroScience, 2017; 39 (3): 251-259.
38. Xiang Ding, Joseph B. Margolick, Sean X. Leng. T-Cell Immunity against Cytomegalovirus in Older Adults. Handbook of Immunosenescence, 2017: 1-14
39. Sean X. Leng, Xiaohong Liu, Jeffery B. Halter. A Chinese Home Care Model for Frail Elderly Integrating Geriatrics, Home Service, and Technology. Innovation in Aging, 2017; 1 (1): 1048–1049.
40. Xiaohong Liu, Minglei. Zhu, Lin Kang. The Role of Geriatrics Interdisciplinary Team in Home Care for the Frail Elderly in Beijing, China. Innovation in Aging, 2017; 1 (1): 1049.
41. Qianli Xue, Huanle Yang, Huifen Li, Peter M. Abadir, Tyesha N. Burks, Lauren G. Koch, Steven L. Britton, Joshua Carlson, Laura Chen, Jeremy D. Walston, Sean X. Leng. Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats. Aging, 2016; 8 (3): 769 – 776.
42. Sean X. Leng, Xiaoying Li. Introduction of Abstracts to be Presented at the Fifth Chinese Congress on Gerontology and Health Industry. Journal of the American Geriatric Society, 2016; 64 (s2): s315- s316.
43. Genxiang Mao, Huifen Li, Xiang Ding, Xin Meng, Guofu Wang, Sean X. Leng. Suppressive effects of sirtinol on human cytomegalovirus (hCMV) infection and hCMV-induced activation of molecular mechanisms of senescence and production of reactive oxygen species. Mechanisms of Ageing and Development, 2016; 158: 62 – 69.
44. Huifen Li, Genxiang Mao, Joshua Carlson, Sean X. Leng. A novel flow cytometry-based tool for determining the efficiency of human cytomegalovirus infection in THP-1 derived macrophages. Journal of Virological Methods, 2015; 221 (1): 127 – 130.
45. Jirong Yue, Tammy T. Hshieh, Sharon K. Inouye. Hospital Elder Life Program (HELP). Geriatrics Models of Care, 2015: 25-37. (book, doesn’t have volume and issue number )
46. Sean X. Leng, Joseph B. Margolick. Understanding Frailty, Aging, and Inflammation in HIV Infection. Current HIV/AIDS Reports, 2015; 12 (1): 22 – 35.
47. Sean X. Leng, Stewart Dandorf, Huifen Li, Joshua Carlson, Jessica Hui, Shruti H. Mehta, Damani Piggott, Salequl Islam, Bhavish Manwani, Gregory D Kirk. Associations of Circulating Soluble Tumor Necrosis Factor-α Receptors 1 and 2 with Interleukin-6 Levels in an Aging Cohort of Injection Drug Users with or at High Risk for HIV Infection. AIDS Research and Human Retroviruses, 2015; 31 (12): 1257-1264.
48. Sean X. Leng, Xiaoying Li. Introduction of Abstracts to be Presented at the Fourth Chinese Congress on Gerontology and Health Industry. Journal of the American Geriatric Society, 2015; 63 (s2): s321- s322.
49. Sean X. Leng, Jennie Chin Hansen, Xiaoying Li. Introduction of Abstracts to be Presented at the Third Chinese Congress on Gerontology and Health Industry. Journal of the American Geriatric Society, 2014; 62 (s2): s333- s334.
50. Huifen Li, Peter Weng, Kevin Najarroa, Qianli Xue, Richard D.Sembab, Joseph Margolick, Sean X.Leng. Chronic CMV infection in older women: Longitudinal comparisons of CMV DNA in peripheral monocytes, anti-CMV IgG titers, serum IL-6 levels, and CMV pp65 (NLV)-specific CD8+ T-cell frequencies with twelve-year follow-up. Experimental Gerontology, 2014; 54: 84-89.
51. Xujiao Chen, Genxiang Mao, Sean X Leng. Frailty syndrome: an overview. Clinical Interventions in Aging, 2014; 9: 433-441.
52. Sean X. Leng, Jennie Chin Hansen, Xiaoying Li. Introduction of Abstracts to be Presented at the Second Chinese Congress on Gerontology and Health Industry. Journal of the American Geriatric Society, 2013; 61 (s3): s307- s308.

Dermatology: 23

1. Wei Li, Xiaoqiang Xu, He Wen, Zhifeng Wang, Chao Ding, Xiaochun Liu, YingxiaGao, Huichun Su, Jingxi Zhang, Yue Han, Yan Xia, Xiaokai Wang, Heng GU, and XuYao. Inverse Association between the Skin and Oral Microbiota in Atopic Dermatitis. Journal of Investigative Dermatology. 2019; 139 (8): 1779-1787.
2. Tian Zhu,Yiman Wang, Hongzhong Jin, and Li Li. The role of exosome in autoimmune connective tissue disease. Annals of Medicine. 2019; 51 (2).
3. Yanan Wang, Xuming Mao, Di Wang, Christoph M. Hammers3 Aimee S. Payne, Yiman Wang, Hongzhong Jin, Bin Peng, and Li Li. Anti-BP180 Autoantibodies Are Present in Stroke and Recognize Human Cutaneous BP180 and BP180-NC16A. Frontiers in Immunology. 2019; 10: 236.
4. Wenling Zhao, Yiman Wang, Jing Yuan, Yueping Zeng, and Li Li. Alzheimer’s disease identified in a patient with bullous pemphigoid by dementia screening scales. Chinese Medical Journal. 2019; 132 (13): 1619-1620.
5. Yiman Wang, Yueping Zeng, Wenling Zhao, Yuehua Liu, and Li Li. Hailey-Hailey disease with lichenoid lesions around the anus. Chinese Medical Journal. 2019; 132 (6): 738-740.
6. Chenchen Xu, Jie Liu, Tao Wang, Yixin Luo and Yuehua Liu. Dermoscopic patterns of early-stage mycosis fungoides in a Chinese population. Clinical and Experimental Dermatology. 2018; 44 (2): 169-175.
7. Yiman Wang, Wenling Zhao, Yueping Zeng, Li Li, and Hongzhong Jin. Multiple keratoacanthoma centrifugum marginatum—a case report and systematic review. Translational Cancer Research. 2018; 7 (6).
8. Tian Zhu, Wenling Zhao, Yueping, Zeng, Yuehua Liu, Hongzhong Jin, and Li Li. Systemic sclerosis-rheumatoid arthritis overlap syndrome complicated with Sweet’s syndrome. Clinical Rheumatology. 2018; 37 (8): 228 -2284.
9. Tian Zhu, Donglai Ma, Yueping Zeng, L. Song, Li Li. Bullous pemphigoid associated with silicosis. Journal of the European Academy of Dermatology and Venereology, 2018; 32 (1): e1-e2.
10. Yiman Wang, Xuming Mao, Yanhong Wang, Yueping Zeng, Yidi Liu, Hongzhong Jin, and Li Li. Relapse of bullous pemphigoid: an update on this stubborn clinical problem. Annals of Medicine. 2018; 50(3).
11. Chunying Xiao, Zhenlai Zhua, Shuhong Suna, Jixin Gao, Meng Fua, Yufeng Liu, Gang Wang, XuYao, and Wei Li. Activation of Langerhans cells promotes the inflammation in imiquimod-induced psoriasis-like dermatitis. Journal of Dermatology Science. 2017; 85(3): 170-177.
12. Yu Zhang, Yang Luo, Yue Han, Rong Tian, Wei Li, Xu Yao. Non-bullous lesions as the first manifestation of bullous pemphigoid: A retrospective analysis of 181 cases. The Journal of Dermatology, 2017; 44(7): 742 -746.
13. Yixin Luo and Jie Liu. Image Gallery: Verrucous porokeratosis with characteristic histopathological and dermoscopic feature. British Journal of Dermatology, 2017; 176 (4): e38.
14. Chenchen Xu, Dan Zhou, Yixin Luo, Shuai Guo, Tao Wang, Jie Liu, Yuehua Liu and Zhili Li.Tissue and serum lipidome shows altered lipid composition with diagnostic potential in mycosis fungoides. Oncotarget, 2017; 8 (29): 48041 – 48050.
15. Yixin Luo and Jie Liu. Image Gallery: Moth-eaten alopecia as the only cutaneous symptom of acquired secondary syphilis in a 2-year-old boy. British Journal of Dermatology, 2017; 177(5) : e227.
16. Tian Zhu, Tao Wang, Dongkai Ma, Yanan Wang, and Li Li. A Case of Pagetoid Bowen’s Disease. Chinese Medical Journal, 2017; 130 (24): 3023-3024.
17. Yixin Luo, Jie Liu. Multiple plaques, slack skin, and ulcers. Journal of the American Academy Dermatology, 2016; 75(6): e203 – e206.
18. Angela J. Argyropoulos, Patrick Robichaud, Rebecca Mutesi Balimunkwe, Gary J. Fisher, Craig Hammerberg, Yan Yan, Taihao Quan. Alterations of Dermal Connective Tissue Collagen in Diabetes: Molecular Basis of Aged-Appearing Skin. PLOS ONE Journal, 2016;11(4): e0153806
19. Trupta Purohit, Tianyuan He, Zhaoping Qin, Ting Li, Gary J. Fisher, Yan Yan, John J. Voorhees, Taihao Quan. Smad3-dependent regulation of type I collagen in human dermal fibroblasts: Impact on human skin connective tissue aging. Journal of Dermatological Science, 2016; 83(1): 80-85.
20. Barbara A. Gilchrest. Introduction to the JID Workshop in Shanghai. Journal of Investigative Dermatology Symposium Proceeding, 2015 17(1): 1-6.
21. Jouni Uitto, Gang Wang. Molecular Genetics of Heritable Skin Diseases: Pseudoxanthoma Elasticum as a Paradigm of China-US Collaboration. Journal of Investigative Dermatology Symposium Proceeding, 2015; 17 (1): 20- 21.
22. Liang Jin, Qiujie Jiang, Zhengsheng Wu, Changxia Shao, Yong Zhou, Luting Yang, Jouni Uitto and Gang Wang. Genetic Heterogeneity of Pseudoxanthoma Elasticum: The Chinese Signature Profile of ABCC6 and ENPP1 Mutations. Journal of Investigative Dermatology, 2015; 135 (5): 1294 – 1302.
23. Meng Pan, Haiqin Zhu, Renchao Xu. Immune cellular regulation on autoantibody production in pemphigus. The Journal of Dermatology, 2015; 42 (1): 11 – 17.

Stem Cell Research and Regenerative Medicine (Former: Hematology): 20

1. Elizabeth Cortez-Toledo, Melanie Rose, Emmanuel Agu, Heather Dahlenburg, Wei Yao, Jan A. Nolta and Ping Zhou. Enhancing Retention of Human Bone Marrow Mesenchymal Stem Cells with Prosurvival Factors Promotes Angiogenesis in a Mouse Model of Limb Ischemia. Stem Cells and Development. 2019; 28 (2).
2. Zhimei Cai, Shuo Liu, ,Jie Zi, Jinlong Ma,  and Zheng Ge. A case of primary gastric diffuse large B-cell lymphoma occurring in chronic myeloid leukemia. OncoTargets and Therapy. 2019; 12: 5917-5923.
3. Anqi Zhou, Qi Han, Huihui Song, Jie Zi, Jinlong Ma, and Zheng Ge. Efficacy and toxicity of cladribine for the treatment of refractory acute myeloid leukemia: a meta-analysis. Drug Design, Development and Therapy. 2019; 13: 1867-1878.
4. Qi Han, Jinlong Ma,Yan Gu, Huihui Song, Malika Kapadia,Yuka Imamura Kawasawa,SinisaDovat, Chunhua Song, Zheng Ge. RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia. Journal of Cancer. 2019; 10: 3842-3850.
5. Qi Zhang, Qi Han, Jie Zi, Jinlong Ma, Huihui Song, YuluTian, Mary McGrath, Chunhua Song, and Zheng Ge. Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasms. Genes& Diseases. 2019; 6 (3): 276-281.
6. Zhengxu Sun, Kunpeng Wu, Qiwang Lin, He Fei, Hua Jiang, Tong Chen, Yan Yuan. Toll-like receptor 4 protects against irradiation-induced hematopoietic injury by promoting granulopoiesis and alleviating marrow adipogenesis. Biochemical and Biophysical Research Communication. 2019; online.
7. Pengfei Li, Mengyao Wu, Qiwang Lin, Shu Wang, Tong Chen and Hua Jiang. Key genes and integrated modules in hematopoietic differentiation of human embryonic stem cells: a comprehensive bioinformatic analysis. Stem Cell Research & Therapy, 2018: (9):301
8. Jiaojiao Hu, Qi Han, Yan Gu, Jinlong Ma, Mary McGrath, Fengchang Qiao, Baoan Chen, Chunhua Song, and Zheng Ge. Circular RNA PVT1 expression and its roles in acute lymphoblastic leukemia. 2018; 10 (6).
9. Zheng Ge, Yan Gu, Qi Han, Justin Sloane, Qinyu Ge, Goufeng Gao, Jinlong Ma, Huihui Song, Jiaojiao Hu, Baoan Chen, Sinisa Dovat and Chunhua Song. Plant homeodomain finger protein 2 as a novel IKAROS target in acute lymphoblastic leukemia. Epigenomicts, 2018;10(1):59-69
10. Xilian Zhou, Yan Gu, Qi Han, Mario Soliman, Chunhua Song, and Zheng Ge. Coexistence of EZH2, NOTCH1, IL7R, and PHF6 Mutations in Adult T-cell Acute Lymphoblastic Leukemia. Turkish Journal of Hematology, 2017; 34(4): 366 – 368.
11. Xiaosu Zhao, Xiangyu Zhao, Mingrui Huo, Qiaozhen Fan, Xuying Pei, Yu Wang, Xiaohui Zhang, Lanping Xu, Xiaojun Huang,  Kaiyan Liu,  and Yingjun Chang. Donor-Specific Anti-Human Leukocyte Antigen Antibodies Predict Prolonged Isolated Thrombocytopenia and Inferior Outcomes of Haploidentical Hematopoietic Stem Cell Transplantation. Journal of Immunology Research, 2017; 2017:1043836
12. Yang Song. Minmin Shi, Yuanyuan Zhang, Xiaodong Mo, Yu Wang, Xiaohui Zhang, Lanping Xu, Xiaojun Huang, Yuan Kong. Abnormalities of the Bone Marrow Immune Microenvironment in Patients with Prolonged Isolated Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 2017; 23 (6): 906-912.
13. YutongWang, Yuan Kong, Yang Song, Wei Han, Yuanyuan Zhang, Xiaohui Zhang, Yingjun Chang, Zhengfan Jiang, and Xiaojun Huang. Increased Type 1 Immune Response in the Bone Marrow Immune Microenvironment of Patients with Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 2016; 22 (8): 1376-1382.
14. Yang Song, Yutong Wang, Xiaojun Huang, Yuan Kong. Abnormalities of the bone marrow immune microenvironment in patients with immune thrombocytopenia. Annals of Hematology, 2016; 95(6): 959 -965.
15. Xiangyu Zhao, Feng Gao, Xiaohui Zhang, Yu Wang, Lanping Xu, Kaiyan Liu, Xiaosu Zhao, Yingjun Chang, Han Wei, Huan Chen, Yuhong Chen, Zhengfan Jiang, Xiaojun Huang. Improved clinical outcomes of rhG-CSF-mobilized blood and marrow haploidentical transplantation compared to propensity score-matched rhG-CSF-primed peripheral blood stem cell haploidentical transplantation: a multicenter study. Science China Life Sciences, 2016; 59 (11): 1149-1148.
16. Yuan Kong, Yang Song, Yue Hu, Minmin Shi, Yutong Wang, Yu Wang, Xiaohui Zhang, Lanping Xu, Kaiyan Liu, Hongkui Deng, Xiaojun Huang. Increased reactive oxygen species and exhaustion of quiescent CD34-positive bone marrow cells may contribute to poor graft function after allotransplants. Oncotarget, 2016; 7(21): 30892 – 30906.
17. Xiangyu Zhao, Xiaosu Zhao, Yutong Wang, Yingjun Chang, Lanping Xu, Xiaohui Zhang, Yu Wang, Yuhong Chen, Wei Han, Huan Chen, Chenhua Yan, Fengrong Wang, Jingzhi Wang, Yuqian Sun, Feifei Tang, Haixia Fu, Kaiyan Liu, Xiaojun Huang. Prophylactic use of low-dose interleukin-2 early post-transplantation: a randomized study. The Lancet, 2015; 386 (1): S7.
18. Yingjun Chang, Xiangyu Zhao, Lanping Xu, Xiaohui Zhang, Yu Wang, Wei Han, Huan Chen, Fengrong Wang, Xiaodong Mo, Yuanyuan Zhang, Mingrui Huo, Xiaosu Zhao, Yuan Kong, Kaiyan Liu, and Xiaojun Huang. Donor-specific anti-human leukocyte antigen antibodies were associated with primary graft failure after unmanipulated haploidentical blood and marrow transplantation: a prospective study with randomly assigned training and validation sets. Journal of Hematology & Oncology, 2015; 8:84.
19. Xiangyu Zhao, Xiaosu Zhao, Yutong Wang, Yingjun Chang, Lanping Xu, Xiaohui Zhang, Yu Wang, Yuhong Chen, Wei Han, Huan Chen, Chenhua Yan, Fengrong Wang, Jingzhi Wang, Yuqian Sun, Feifei Tang, Haixia Fu, Kaiyan Liu, Xiaojun Huang. Higher frequency of regulatory T cells in granulocyte colony-stimulating factor (G-CSF)-primed bone marrow grafts compared with G-CSF-primed peripheral blood grafts. Journal of Translational Medicine, 2015 13:145.
20. Xiangyu Zhao, Yingjun Chang, Xiaosu Zhao, Lanping Xu, Xiaohui Zhang, Kaiyan Liu, Dan Li, Xiaojun Huang. Recipient expression of ligands for donor inhibitory KIRs enhances NK-cell function to control leukemic relapse after haploidentical transplantation. European Journal of Immunology, 2015;45(8):2396-408.

Reproductive Medicine: 6

1. Ling Deng, Xuelan Li, Desheng Ye, Christophe Blockeel, Xingyu Zhou, Shiling Chen, and Xin Chen. A Second Dose of GnRHa in Combination with Luteal GnRH Antagonist May Eliminate Ovarian Hyperstimulation Syndrome in Women with ≥30 Follicles Measuring ≥11 mm in Diameter on Trigger Day and/or Pre-trigger Peak Estradiol Exceeding 10 000 pg/mL.  Current Medical Science. 2019; 39 (2): 278-284.
2. Yong Chen, Jing Wang, Yanhong Fan, Chunrong Qin, Xi Xia, JoshuaJohnson, Amanda N.Kallen. Absence of the long noncoding RNA H19 results in aberrant ovarian STAR and progesterone production. Molecular and Cellular Endocrinology. 2019; 490: 15-20.
3. Xi Xia and Amanda N. Kallen. Serum H19 expression is decreased in women with diminished ovarian reserve. Fertility and Sterility. 2018; 110 (4): e100.
4. Xin Chen, Shuxian Feng, Pingping Guo, Yuxia He, Yudong Liu, Desheng Ye, Shiling Chen. Does lower dose of long-acting triptorelin maintain pituitary suppression and produce good live birth rate in long down-regulation protocol for in-vitro fertilization? Journal of Huazhong University of Science and Technology [Medical Sciences], 2016; 36 (2): 215-220.
5. Xin Chen, Yuan Huang, Pingping Guo, DeshengYe, Lijuan Xu, Shiling Chen. The association between serum β-hCG on day 24 of pregnancy and ongoing pregnancy in frozen embryo transfer cycles. International Journal of Gynecology & Obstetrics, 2016; 134 (3):  278 – 281.
6. Xin Chen, Shiling Chen, Desheng Ye, Yudong Liu, Yuxia He, Xiaolong Tian, Lijuan Xu, Ting Tao. Retrospective analysis of reproductive outcomes in women with primary ovarian insufficiency showing intermittent follicular development. Reproductive Bio-Medicine Online. 2016; 32(4): 472-433.

Translational Medicine: 15

1. Nidan Qiao. Deep Learning and medical big data. [Book]. (to be published in December 2019)
2. Nidan Qiao, Mengju Song, Zhao Ye, Wenqiang He, Zengyi Ma, Yongfei Wang, Yuyan Zhang, Xuefei Shou. Deep Learning for Automatically Visual Evoked Potential Classification during Surgical Decompression of Sellar Region Tumors. Translational Vision Science & Technology.(accepted)
3. Xiang Zhou and Nidan Qiao. Association of Cortisol Levels With Neuropsychiatric Functions: A Mendelian Randomization Analysis. Frontier in Neurology. 2019; 10:564.
4. Weisheng Chen, Jiachen Lin, Lianlei Wang, Xiaoxin Li, Sen Zhao, Jiaqi Liu, Zeynep C. Akdemir, Yanxue Zhao, Renqian Du, Yongyu Ye, Xiaofei Song, Yuanqiang Zhang, Zihui Yan, Xinzhuang Yang, Mao Lin, Jianxiong Shen, Shengru Wang, Na Gao, Ying Yang, Ying Liu, Wenli Li, Jia Liu, Na Zhang, Xu Yang, Yuan Xu, Jianguo Zhang, Mauricio R. Delgado, Jennifer E. Posey, Guixing Qiu, Jonathan J. Rios, Pengfei Liu, Carol A. Wise, Feng Zhang, Zhihong Wu, James R. Lupski, and Nan Wu. TBX6 missense variants expand the mutational spectrum in a non-Mendelian inheritance disease. Human Mutation. 2019; Early view.
5. Sen Zhao, Yuanqiang Zhang, Weisheng Chen, Shengru Wang, Pengfei Liu, Shuyang Zhang, Carol A Wise, James R Lupski, Zhihong Wu, Guixing Qiu, Jianguo Zhang, NanWu. Diagnostic yield and clinical effects of exome sequencing analysis in patients with early-onset scoliosis. The Lancet .2019; 394(1): s79.
6. Yi han Cao, Chen Lia, Wenrui Xu, Xia Wu, Xiaochuan Sun, Weihong Zhang, Hongli Jing, Zhaoqi Gu, Siyi Yuan, Li Li, Yuzhi Zuo, Jinhe Liu, Zhihong Wu, Zhenhua Dong, Weixin Hao, Wen Zhang, and NanWu. Spinal and sacroiliac involvement in SAPHO syndrome: A single center study of a cohort of 354 patients. Seminars in Arthritis and Rheumatism. 2019; 48 (6): 990-996.
7. Qiming Xu, Nan Wu, Lijia Cui, Mao Lin, Thirumal Kumar, George Priya Doss, Zhihong Wu, Jianxiong Shen,  Xiangjian Song, and Guixing Qiu. Comparative analysis of the two extremes of FLNB-mutated autosomal dominant disease spectrum: from clinical phenotypes to cellular and molecular findings. American Journal of Translational Research.  2018; 10 (5): 1400-1412.
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